Best Enterprise AI That Works Without Microsoft 365

For a company that runs on Google Workspace, Slack and Salesforce, the strongest enterprise AI options are Coworker, Glean, ChatGPT Enterprise and Gemini Enterprise. Coworker is a context layer for enterprise AI: it connects 50+ work tools, builds a permission-aware company graph (OM2) and runs agents that act across them, inside Coworker or Claude, ChatGPT and Cursor via Coworker MCP. Microsoft 365 Copilot can reach some non-Microsoft data through admin-built connectors, but it is designed around Microsoft 365.

Microsoft 365 Copilot is excellent inside Microsoft 365. It drafts in Word, analyzes Excel data, triages Outlook and recaps Teams meetings better than almost anything else. The question for a mixed-stack company is different: what happens when the CRM is Salesforce, the chat is Slack, the tickets are in Jira and the docs are in Google Drive? This guide compares the options on that question, using each vendor's own documentation, checked on October 14, 2026.

Does Microsoft 365 Copilot work with Salesforce, Slack and Google Workspace?

Partly. Microsoft 365 Copilot is grounded in Microsoft Graph, and non-Microsoft data reaches it through Microsoft 365 Copilot connectors that an admin sets up. Microsoft lists more than 100 prebuilt connectors, including Salesforce, ServiceNow, Confluence and Google services. Copilot itself still lives in Word, Excel, Outlook and Teams.

That design has three practical consequences for a mixed-stack team:

• Each outside tool is an admin project. Salesforce, Confluence or Google Drive content shows up in Copilot only after someone configures and maintains a connector for it, so check the connectors gallery for every tool you rely on.
• The work surface is Microsoft's. People use Copilot inside Microsoft 365 apps and Teams. A team that lives in Slack and Google Docs has to go to Copilot rather than have it where they already work.
• Pricing assumes Microsoft 365. Copilot is $30 per user per month, paid yearly, on top of a qualifying Microsoft 365 plan, per Microsoft's pricing page. A company standardized on Google Workspace pays for a suite it does not otherwise use.

None of this is a criticism of Copilot's AI quality. Inside Microsoft 365 it performs well.

For companies that are almost entirely on Microsoft 365, Copilot is usually the right choice. For everyone else, the better question is which platform treats your actual tools as first-class sources.

What are the best Microsoft 365 Copilot alternatives for Google Workspace, Slack and Salesforce?

The best Microsoft 365 Copilot alternatives for a Google Workspace, Slack and Salesforce company are Coworker for agents that act across those tools on a shared company graph, Glean for enterprise search at scale, ChatGPT Enterprise for a general assistant with company knowledge, and Gemini Enterprise for Google-first organizations. Here is how they compare, checked on October 14, 2026.

Sources: Microsoft connectors gallery, Glean connectors, Glean actions docs, Vendr Glean data, OpenAI company knowledge release notes, Gemini Enterprise, Guru pricing.

Glean is the strongest option when the main problem is finding information across many tools. It indexes Slack, Google Drive, Salesforce, Jira and hundreds of other sources with permission-aware ranking, and its agents can now take actions such as creating a Jira issue or updating a Salesforce record. The trade-offs are cost and rollout: Glean is quote-only, buyers report seat minimums of 100 to 250 users, and Glean's documentation puts a standard deployment at 1 to 3 weeks. Compare Glean vs Coworker.

Notion AI fits teams whose documentation already lives in Notion. On Business and Enterprise plans, its Enterprise Search also searches connected apps such as Slack, Google Drive, Jira and GitHub. It is strongest as a workspace assistant rather than as an agent that works inside your CRM.

Guru is built to keep company knowledge verified. Its Knowledge Agents give cited, permission-aware answers and its MCP server delivers that knowledge to Claude, ChatGPT and other tools. It is not designed to update CRM records or tickets in other systems.

What "Works Without M365" Actually Means

When evaluating enterprise AI that works without Microsoft 365, there are three tiers of capability:

Tier 1: Search across tools. The AI can find information in Salesforce, Slack, Jira and other non-Microsoft apps. Every platform in the table above does this to some degree, and Glean does it at the largest scale.

Tier 2: Understand relationships across tools. The AI knows that a Slack thread about a project relates to a Jira epic, a Google Doc spec and a Salesforce opportunity. This is where a company graph matters. Coworker's OM2 maps people, projects, deals and relationships across your connected tools into one graph and keeps it current as new data arrives.

Tier 3: Execute actions across tools. The AI updates CRM fields after a meeting, creates Jira tickets from a Slack conversation and drafts follow-ups with full cross-tool context. Coworker, Glean and Gemini Enterprise all support actions in other tools, so put the exact actions your team needs into the demo.

Coworker covers all three tiers. It connects to 50+ tools, maintains OM2 continuously, and runs agents across Salesforce, Jira, Slack, Google Drive and HubSpot. In Coworker's published benchmark, Claude with OM2 used 89.1% fewer tokens than Claude with its native connectors on retrieval-heavy tasks (a statistically significant result comparing Coworker MCP with Claude's native tooling).

Which enterprise AI keeps Google Drive, SharePoint and Slack permissions intact?

Coworker, Glean, ChatGPT Enterprise, Gemini Enterprise and Microsoft 365 Copilot all inherit permissions from the source tools they connect to. Coworker applies source permissions to every fact in its OM2 company graph, so a person or agent only recalls what they can already see in Google Drive, SharePoint or Slack.

How to Evaluate Enterprise AI for a Non-M365 Stack

Before choosing a platform, run this checklist:

1. List your critical tools. Write down every app your team uses daily. If Salesforce, Slack, Jira or Google Workspace is on that list, check exactly how each platform connects to it and who maintains that connection.
2. Check native integrations, not just connector counts. "1,000+ integrations via Zapier" is not the same as native connectors with deep data access. Ask whether the AI can read and write to your specific tools.
3. Test cross-tool queries. Ask the platform: "What is the status of the Acme deal, including related Slack conversations, open Jira tickets, and recent meeting notes?" If it cannot answer from multiple sources in one response, it is not solving the mixed-stack problem.
4. Verify execution capabilities. Can the AI update Salesforce after analyzing a Slack thread? Can it create a Jira ticket from a meeting transcript? Search alone is not enough.
5. Run a POC with real data. Coworker offers a 48-hour proof of concept with your actual tools connected. Test with real workflows, not demo data.

For a direct head-to-head on search across Salesforce, Jira, Confluence and Slack, see Glean vs Microsoft 365 Copilot.

Frequently asked questions

Does Microsoft Copilot work with Salesforce?

Partly. Microsoft 365 Copilot can search Salesforce data once an admin sets up the Salesforce Copilot connector, which indexes that content into Microsoft Graph. Copilot itself works inside Microsoft 365 apps. Coworker connects to Salesforce natively and can read and update records, with your approval on every write. See the full Copilot comparison.

What is the best Microsoft Copilot alternative for enterprise teams?

It depends on your primary need. For search at very large scale, Glean is strong. For a Google-first company, Gemini Enterprise is the natural fit. For agents that act across Salesforce, Slack, Jira and Google Drive on a shared company graph, and that also work inside Claude, ChatGPT and Cursor, Coworker is the strongest option, and it needs no Microsoft license. Compare all options.

Can Glean replace Microsoft Copilot for non-M365 companies?

Often, yes. Glean works across many tools that Copilot only reaches through connectors, including Salesforce, Slack, Jira and Google Workspace, and its agents can take actions such as creating Jira issues. Its trade-offs are quote-only pricing, seat minimums and a 1 to 3 week standard deployment. Coworker is the option to compare if you also want the same company context inside Claude or ChatGPT. Compare Glean vs Coworker.

How much does enterprise AI cost without Microsoft 365?

Microsoft 365 Copilot is $30 per user per month on top of a Microsoft 365 plan. Gemini Enterprise Business starts at $21 per seat per month. Glean, ChatGPT Enterprise and Guru are quote-only; Vendr's buyer data puts Glean's median contract at about $98,890 a year. Coworker is priced for your team on a call: book a demo for a quote.

How long does it take to deploy an AI platform that works with Salesforce, Slack, and Jira?

It ranges from days to weeks. Glean's documentation puts a standard deployment at 1 to 3 weeks and large organizations at 3 to 4 weeks or more. Coworker runs a 48-hour proof of concept on your real data, and standard onboarding takes 2 to 5 business days. Coworker is SOC 2 Type II, GDPR and CASA Tier 2 compliant.

Glean vs Microsoft 365 Copilot: which is better for search across Salesforce, Jira, Confluence and Slack?

Glean is usually better when knowledge is spread across many non-Microsoft tools, because it connects to 250+ sources out of the box. Microsoft 365 Copilot is better when most work lives in Outlook, Teams and SharePoint. Coworker is the third option when you want agents that act across those tools.

Related Reading

• Microsoft Copilot Alternative for Enterprise Teams - full comparison of Copilot vs Coworker AI
• Glean Alternative for Enterprise Teams - Coworker vs Glean, side by side
• How to Stop Context Switching Across 10+ Enterprise Tools - the real cost of tool fragmentation
• The Enterprise AI Buyer's Checklist - 10 questions to ask before choosing a platform
• AI That Executes Work vs AI That Just Answers Questions - why search alone is not enough
• Best Microsoft Copilot Alternatives - six options compared
• What Is a Context Layer? - the category Coworker sits in

Running a mixed tool stack? Book a demo and see Coworker work across your own Salesforce, Slack and Jira data.